Peer tutoring is a commonly used out-of-class support system that has potential benefits for both students who are receiving academic support and for students who are providing the academic support. Designing peer tutoring support structures that promote engagement of students in the learning process provides an opportunity to improve student course performance and ultimately student retention in chemistry. In this symposium, effective practices for developing, evaluating, and maintaining peer tutoring in chemistry will be explored. Important questions include: What initiatives have been successful in encouraging students to consistently utilize peer tutoring? What types of training for peer tutors have been effective in helping them engage students in the learning process? What are cost-effective and scalable approaches for meaningful tutoring interactions? What is the impact of different peer tutoring structures on student learning gains? What is the impact of peer tutoring practices on student retention in chemistry? How can technology be utilized to support both tutors and students seeking assistance? Do effective peer tutoring approaches vary by institutional type or course level? Attendees will be encouraged to actively participate in the discussion and share their experiences in building and maintaining effective tutoring practices.